A growing body of evidence suggests that long-term survivors with one of the more common forms of adult cancer report similar quality of life (QOL) to the general population. However, specific concerns have been identified (sexual dysfunction, fatigue, distress) in this population. Also, less is known about survivors of adult non-Hodgkin lymphoma (NHL), a disease often marked by alternating periods of disease and remission. Therefore, this study compares the QOL status of individuals who report having active NHL with those who are disease-free short-term (2–4 years post-diagnosis; STS) and long-term (≥5 years post-diagnosis; LTS) survivors.