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Reduced Serologic Sensitivity to Influenza A Virus Illness Among Inactivated Influenza Vaccines

Mark G. Thompson, Manjusha J. Gaglani, Allison L. Naleway, Samuel H. Dowella, Sarah Spencer, Sarah Ball, Min Levine, Alicia Fry

Article

June 2, 2016

This article examines data collected as part of a study to assess the effectiveness of influenza vaccination among health care professionals (HCPs). Studying a cohort of HCPs in Oregon and Texas, authors compared the sensitivity of two diagnostic methods for measuring immune response.  Findings confirm earlier research that reliance on serologic outcomes alone may overestimate the effectiveness of flu vaccination. Authors discuss implications and areas for future research.

Focus Areas
Regions
North America