Despite a marked decline in HIV and AIDS cases since the early-mid 2000s, significant challenges for St. Vincent and the Grenadines' response remain.  Among these, St. Vincent and the Grenadines faces an imminent decline in donor funding and domestic reprioritization in favor of chronic and non-communicable diseases.  Its Ministry of Health must address these obstacles by mobilizing and prioritizing domestic resources for HIV and AIDS in an equitable, efficient, and sustainable manner.  The report assists in this endevor by modeling three potential investment scenarios and their implications for the HIV and AIDS epidemic and costs.  Findings indicate that while each of the scenarios offer markedly different strategies for addressing St. Vincent and the Grenadines’ HIV and AIDS epidemic and thus result in different impacts, all three will require additional resources beyond what is expected to be available.