This page is optimized for a taller screen. Please rotate your device or increase the size of your browser window.

Supporting Development, Dissemination and Implementation of the CDC Opioid Prescribing Guidelines


  • Doctors lacked consensus on prescribing opioids, with wide geographic variations.
  • Abt helped devise an opioid prescribing guideline.
  • Abt is developing quality improvement interventions for the prescribing guideline.
The Challenge

Nearly 50,000 persons died of opioid overdoses in 2017, which contributed to the first-ever decline in working-age Americans’ life expectancy. A 2012 Abt Associates study found wide geographic variation in opioid prescribing in the United States, indicating a lack of consensus among doctors in how to manage non-cancer pain outside of palliative and end-of-life care.

The Approach

To remedy this, the Centers for Disease Control and Prevention (CDC) undertook several efforts to provide health care providers with evidence-based guidance. CDC contracted with Abt to provide research support, including conducting literature reviews, synthesizing research, assembling evidence tables, and providing editorial support for draft clinical recommendations. In March 2016, the CDC issued the CDC Guideline for Prescribing Opioids for Chronic Pain.

The Results

Because guidelines are not self-executing, the CDC’s National Center for Injury Prevention and Control contracted with Abt for three related projects. The first was to develop and pilot a coordinated care plan for opioid prescribing: CDC Quality Improvement and Care Coordination. Another is to develop quality improvement (QI) measures for opioid therapy in outpatient primary care settings and to support a QI collaborative with a dozen large healthcare systems.  Finally, Abt is developing clinical decision support tools and implementing them in four pilot healthcare systems’ electronic health records to assist physicians in following best practices and the CDC’s guideline recommendations.


CDC Quality Improvement and Care Coordination: Implementing the CDC Guideline for Prescribing Opioids for Chronic Pain

Geographic Variation and Disparity in Stimulant Treatment of Adults and Children in the United States in 2008

North America