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Tracking COVID-19 in High-Risk Workers


  • Gather COVID-19 data from healthcare personnel, first responders and frontline workers
  • Assess illness characterization, asymptomatic infection rates, viral shedding, and vaccine effectiveness
  • Results are ongoing.
The Challenge

CDC needs timely information on COVID-19 illness characterization and correlates of protection in this highly-exposed cohort. CDC also needs data on rates of asymptomatic infection and re-infection and viral shedding. Since this population is among the first to receive a vaccine, CDC is also evaluating COVID-19 vaccine effectiveness. Setting up the structure for gathering the data and then gathering it must be done rapidly to inform policy decisions.

The Approach

The Research on the Epidemiology of SARS-CoV-2 in Essential Response Personnel (RECOVER) study is a prospective, longitudinal cohort study of approximately 3,500 healthcare personnel, first responders, and frontline workers from six U.S. regions. Abt adapted our existing infrastructures, study protocols, and tools to conduct surveillance activities to assess risk and characterize disease epidemiology of COVID-19. We are partnering with clinical institutions chosen for their history of conducting respiratory virus research. As part of this effort, our study participants are self-collecting a respiratory specimen every week for more than two years.  

The Results

Results are ongoing.